irritated

cause annoyance in; disturb, especially by minor irritations

Mosquitoes buzzing in my ear really bothers me

excite to an abnormal condition, or chafe or inflame

Aspirin irritates my stomach

excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus

irritate the glands of a leaf

aroused to impatience or anger

made an irritated gesture